The challenge

Health economic models are essential for demonstrating value and supporting payer and HTA decision-making. However, traditional model development often requires weeks of manual effort building model structures, linking formulas, and validating calculations before meaningful analysis can begin.

This process can introduce inconsistencies across projects, increase exposure to manual errors, delay market access planning, and limit time for evidence assessment and strategic interpretation.

The solution

Acumetis Model Builder is a web-based platform that generates complete, formula-linked Excel cost-effectiveness and budget impact models in under five minutes. Through a guided interface, users define key model requirements to generate fully editable outputs aligned with international HTA guidance and payer expectations, with no hidden code or locked cells.

By automating model construction and standardising design, Model Builder reduces manual effort, improves consistency, and limits exposure to calculation errors, allowing teams to focus on evidence generation, model optimisation, scenario analysis, and strategic decision-making.

Why Model Builder

Doctor showing patient something on a tablet

Develop working models using placeholder data before all evidence is finalised, then refine inputs, assumptions, and analyses as new information becomes available. This allows teams to explore different approaches, evaluate scenarios, and adapt models to evolving evidence and market access requirements without rebuilding the model from scratch.

Core inputs

Built around six core decisions

Every economic model relies on key decisions that determine how comparisons are structured, type of costs and outcomes are measured, and results are presented.

Model Builder brings these decisions into a consistent framework, helping teams capture treatment benefits, establish a clear economic rationale, and evaluate the robustness of results to support payer and HTA review.

Traditional model build vs. Model Builder

Traditional approach
Model Builder
Several weeks to generate a working model
Complete model generated in under five minutes
Manual formulas and calculation linking
Automated calculations and model assembly
Variable design across projects and teams
Consistent, standardised design framework
Significant analyst time spent on model construction
More time focused on evidence and interpretation
Greater exposure to manual error
Reduced risk through automation

Backed by Global Value and Access expertise

Model Builder is backed by Acumetis’ deep expertise in global value & access, health economics, and evidence strategy. Developed to address the real-world challenges faced by manufacturers, payers, and HTA bodies, it combines proven modelling approaches with automation to help teams generate high-quality, payer-ready economic models faster and more consistently.

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Payer submissions completed
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Economic models developed
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HTA submissions supported
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Countries supported

How Model Builder works

Define the problem

Specify the disease area, intervention, and comparators.

Configure the model

Define perspective, model structure, health states, and time horizon.

Add costs

Specify treatment, health state, and adverse event costs.

Set analyses

Define sensitivity, scenario, and probabilistic analyses.

Generate model

Download a fully editable, formula-linked Excel model in under five minutes.

Refine and customise

Start with placeholder data before evidence is finalised, then refine assumptions and analyses as evidence evolves.

One journey, two model types

Model Builder supports cost-effectiveness and budget impact models through a guided workflow that captures the inputs, assumptions, and analyses required for each approach.

Both model types follow a guided process and generate complete, formula-linked Excel models with no hidden code or locked cells, ready for download, review, and further customisation.

Cost-effectiveness models
Generate cost-effectiveness models using Markov or partitioned survival structures, with configurable health states and health economic parameters.
KEY FEATURES
Decision problem, perspective, and cost types
Markov or partitioned survival structures
Customizable health states
Time horizon and cycle settings
Quality-of-life inputs
Sensitivity, scenario, and probabilistic analyses
Budget impact models
Generate budget impact models to evaluate the financial impact of an intervention within a defined payer or population context.
KEY FEATURES
Decision problem, perspective, and cost types
Population and epidemiology inputs
Configurable time horizons
Treatment switching and discontinuation assumptions
Dose adjustment options
One-way sensitivity analysis
Get in touch

See Model Builder in action

Discover how Acumetis Model Builder can help your organisation generate payer-ready economic models faster, improve consistency, and redirect analyst time from manual model construction to evidence generation, scenario evaluation, and strategic decision-making.